The diagnosis and treatment of posttransplant lymphoproliferative disorders.

(Prices quoted are in U.S. dollars. Canadian orders will be billed in Canadian funds at the approximate current exchange rate. A small additional charge will be made for postage and handling.) FOREIGN: please refer below for the distributor in your area. Single issue price is $9.95. Second-class postage paid at Chicago, IL and additional mailing offices. All rights reseIved. No part of this publication may be reproduced, stored ill a retrieval system, or transmitted, in any form or by any means~electronic, mechanical, photocopying, recording, or otherwise~without prior written permission from the publisher except in cases described below. The code at the bottom of the first page in this issue indicates the publisher's consent that copies of the article may be made for personal or internal use. This consent is given on the condition that the copier pay the stated per-copy fee through MA 01970) for copying beyond that permitted by Sections 107 or 108 of the United States Copyright Law. This consent does not extend to other kinds of copying, such as copying for general distribution, for advertising or promotional purposes, for creating new collected works, or for resale. India Current Problems in Surgery is listed in Index Medicus, Current Contents (CC), lSlIBioMed) and the SCI. FOREWORD Dr. Thomas Starzl and his colleagues have since their Colorado days spearheaded the recognition of the occurrence of posttransplant lymphoproliferative disorders and in a series of publications have contributed to their understanding and treatment. In this issue of Current Problems in Surgery, Drs. Nalesnik, Makowka, and Starzl have produced a superb and comprehensive monograph on this subject. The article is a tour de force of combined basic and clinical sciences, together with a concrete exposition of the various clinical factors involved from etiology, recognition, and treatment to ultimate outcome. As frightening as these disorders are, the heavy price they exact still turns out to be a tolerable price for the benefits of organ transplantation in the population at risk, particularly in view of the fact, as amply shown in these pages, that with appropriate therapy the tumors may be cured or made to regress, often without sacrifice of the transplanted organ. In what must be considered a complicated subject, much of it at the very forefront of our expanding knowledge in transplantation biology , the authors have created a lucid and readily comprehensible masterpiece. The clinical features of the disease are highlighted by …